Hepatitis A virus-associated acute acalculous cholecystitis in an adult-onset Still’s disease patient: A case report and review of the literature

Table 3 Acute acalculous cholecystitis associated with adult-onset Still’s disease

Ref.	Age/Sex	Symptoms	Physical examination	Vital signs	Ultrasound/CT findings	Bilirubin (total/direct, mg/dL) (0.2-1.2/0-0.3)	AST/ALT (U/I) (10-40/9-50)	WBC (109/L) (3.5-9.5)	Hb (g/dL) (11-15)	Platelets (109/L) (125-350)
Park et al[20], 2004	49/F	Recurrent fever, rash, and polyarthritis. Confused mental status on admission	Icterus, Murphy’s sign (+), enlarged liver and spleen, facial rash, dehydrated tongue, equivocal neck stiffness, purpuras over the limbs, scabs of zoster	T 39 °C, BP 90/60 mmHg, HR 100 bpm, RR 30	Hepatosplenomegaly, thickened gallbladder wall, pericholecystic fluid collection, ileocolitis, right pleural effusion and ascites	3.7/2.8	453/154	7.1	9.5	17
Vallianou et al[21], 2014	28/F	Fever, vomiting, confused mental status, abdominal pain	Severe and diffuse abdominal tenderness	T 40 °C, no peripheral pulse, systolic BP 50 mmHg	Gallbladder enlargement with edema	/	/	/	/	/
Arai et al[8], 2021	21/F	Recurrent fever, rash, polyarthritis, nausea, vomiting, right hypochondriac pain	Rash, enlarged liver and spleen, tenderness in both shoulder and knee joints	T 40 °C	Hepatosplenomegaly, gallbladder enlargement and wall thickening, acalculous, cervical lymphadenopathy	2.15/1.56	763/469	2.3	11	79

AOSD: Adult-onset Still’s disease; AST: Aspartate transaminase; ALT: Alanine aminotransferase; BP: Blood pressure; RR: Respiratory rate; T: Temperature; WBC: White blood cell count; Hb: Hemoglobin; HR: Heart rate.