Clinical manifestations of adult hereditary spherocytosis with novel SPTB gene mutations and hyperjaundice: A case report

Table 1 Patient indicators during treatment

Indicator	Before ERCP	After ERCP	During medication	Before removal of biliary stent	After removal of biliary stent	Before splenectomy	After splenectomy	Recent results
TBIL (μmol/L)	1734.7	1618.1	442.9	83.5	96.4	105.1	31.5	22.5
DBIL (μmol/L)	1146.4	998.0	316.7	13.0	14.8	14.9	7.8	5.5
IBIL (μmol/L)	588.3	828.5	126.2	70.5	81.6	90.2	23.7	17.0
Hb (g/L)	122	110	94	76	72	109	122	139
MCH (pg)	33.1	32.1	34.5	32	35.0	32.0	31
RDW-SD (fL)	66.2	66.4	51.9	64.4	57.2	58.6	55.3	52.7
RET# (× 1012/L)	0.235	0.254	0.260	0.368	0.249	0.231	0.026	0.043
AST (U/L)	37	34	34	14	12	31	47	22.5
ALT (U/L)	103	70	70	18	12	60	54	32.3
ALP (U/L)	359	299.9	299.9	102.0	105.0	169.4	171.7	214.5
GGT (U/L)	264.6	154.2	154.2	29.0	26.7	72.1	176.9	40.2
ALB (g/L)	43.2	39.0	39	45.7	71.7	57.1	47.0	50.1
Crea (μmol/L)	61	91.3	91.3	109.6	107.5	108.6	93.9	81.8
UA (μmol/L)	88	64	64	596	649	620	435	447
TG (mmol/L)	1.96	2.76	2.76	0.95	1.04	1.85	1.50	1.75
LDL-C (mmol/L)	1.91	1.83	1.83	0.94	1.16	1.21	2.21	2.18

Reference ranges: Total bilirubin 9.1-30.1 μmol/L, direct bilirubin 0-6.8 μmol/L, indirect bilirubin 0-19 μmol/L, hemoglobin 120-160 g/L, mean corpuscular hemoglobin 27-31 pg, red blood cell distribution width 39-46 fL, red blood cell distribution width (0.017-0.064) × 10¹²/L, aspartate aminotransferase 1-49 U/L, alanine aminotransferase 1-49 U/L, alkaline phosphatase 20-125 U/L, gamma-glutamyl transpeptidase 3-69 U/L, albumin 32-55 g/L, Crea 44-108 μmol/L, uric acid 125-420 μmol/L, triglyceride 0.8-1.8 mmol/L, low-density lipoprotein 1.55-3.7 mmol/L. TBIL: Total bilirubin; DBIL: Direct bilirubin; IBIL: Indirect bilirubin; Hb: Hemoglobin; MCH: Mean corpuscular hemoglobin; RDW-SD: Red blood cell distribution width; RET: Reticulocyte; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transpeptidase; ALB: Albumin; UA: Uric acid; TG: Triglyceride; LDL-C: Low-density lipoprotein.