Multiple regression analysis of risk factors related to radiation pneumonitis

Table 3 Logistic regression analysis of risk factors for radiation pneumonitis

Factor	B	S.E.	Wald	P	OR	95%CI
Age	-2.232	0.842	7.028	0.008	0.11	0.02-0.48
Tumor type (Lung)
Mammary	-3.038	0.938	8.313	0.001	0.05	0.01-0.26
Esophageal	-3.753	1.075	8.313	< 0.001	0.02	0.00-0.16
History of chemotherapy	3.108	0.854	13.259	< 0.001	22.37	4.85-143.77
FEV1	0.292	0.096	9.199	0.002	1.34	1.13-1.65
DLCO	0.410	0.093	19.226	< 0.001	1.51	1.28-1.85
FEV1/FVC ratio	-0.329	0.119	7.656	0.006	0.72	0.59-0.90
PTV	0.477	0.149	10.206	0.001	1.61	1.23-2.22
MLD	-0.217	0.118	3.377	0.066	0.80	0.65-1.03
Total number of radiation fields	-0.905	0.244	13.812	< 0.001	0.40	0.23-0.62
Vdose	-0.127	0.086	2.189	0.139	0.88	0.74-1.04
NTCP	1.206	0.211	32.636	< 0.001	3.34	2.33-5.41

FEV1: Forced expiratory volume in the first second; DLCO: Carbon monoxide diffusion volume; FVC: Forced vital capacity; PTV: Planned target area; MLD: Mean lung dose; Vdose: Percentage of lung tissue in total lung volume; NTCP: Normal tissue complications.