Multi-organ hereditary hemorrhagic telangiectasia: A case report

Figure 4 The c. 1121G>A mutation does not affect ALK1 gene expression. A: ALK1 protein of the wildtype and the arginine to glutamate substitution at amino acid position 374 (R374Q) groups were detected by immunoblot in HepG2, Hela, and 293T cell lines; B: Immunofluorescence assay was performed to visualize the expression and distribution of ALK1 in Hela and 293T cell lines. WT: Wildtype.