Retrospective Study
Copyright ©The Author(s) 2023.
World J Clin Cases. Oct 6, 2023; 11(28): 6688-6697
Published online Oct 6, 2023. doi: 10.12998/wjcc.v11.i28.6688
Table 4 Diagnostic performance of antibodies detected by chemiluminescence assay and line immunoassay for systemic lupus erythematosus
AntibodiesChemiluminescence method
Line immunoassay
AUC
95%CI
AUC
95%CI
Anti-double-stranded DNA (dsDNA) antibody0.935 0.907-0.9620.905 0.871-0.940
Anti-histone (Histone) antibody0.508 0.436-0.5800.513 0.441-0.585
Anti-nucleosome (Nuc) antibody0.837 0.788-0.8860.829 0.780-0.879
Anti-Smith (Sm) antibody0.941 0.914-0.9680.907 0.872-0.943
Anti-ribosomal P protein (Rib-P) antibody0.776 0.721-0.8310.791 0.738-0.844
Anti-sicca syndrome A (Ro60) antibody0.953 0.931-0.9750.945 0.921-0.969
Anti-sicca syndrome A (Ro52) antibody0.946 0.920-0.9720.929 0.900-0.958
Anti- sicca syndrome (SSB) antibody0.650 0.584-0.7160.661 0.596-0.727
Anti-centromere protein B (Cenp-B) antibody0.811 0.761-0.8610.787 0.733-0.841
Anti-DNA topoisomerase 1 (Scl-70) antibody0.783 0.727-0.8380.740 0.681-0.800
Anti-histidyl tRNA synthetase (Jo-1) antibody0.821 0.769-0.8740.781 0.722-0.841
Anti-mitochondrial M2 (AMA-M2) antibody0.895 0.844-0.9470.920 0.883-0.957