Meta-analysis of outcomes from drug-eluting stent implantation in infrapopliteal arteries

Table 3 Risk bias assessment results of included studies

The domains in RoB 2.0a for RCTs	Scheinert et al[45], 2012	Rastan et al[26], 2012	Bosiers et al[43], 2012	Spreen et al[24], 2017	Konijn et al[25], 2020
1 Randomisation process	Low	Low	Low	Low	Low
2 Deviations from the intended interventions	Low	Low	Low	Low	Low
3 Missing outcome data	Some concerns	Some concerns	High	High	High
4 Measurement of the outcome	Low	Low	Low	Low	Low
5 Selection of the reported result	Low	Low	Low	Low	Low
6 Overall	Some concerns	Some concerns	High	High	High
The domains in ROBINS-Ib for cohort studies	Siablis et al[42], 2009	Karnabatidis et al[44], 2011	Zuzek et al[27], 2022
1 Confounding	Low	Moderate	Moderate
2 Selection of participants	Low	Low	Low
3 Classification of interventions	Low	Low	Low
4 Deviations from intended interventions	Low	Low	Moderate
5 Missing outcome data	Moderate	Moderate	Moderate
6 Measurement of outcomes	Moderate	Moderate	Moderate
7 Selection of the reported result	Low	Low	Low
8 Overall	Moderate	Moderate	Moderate

^aThe risk is graded into 3 levels: low: some concerns: and high.

^bThe risk is graded into 5 levels: low: moderate: serious: critical: and no information. RoB: Risk of bias tool; RCT: Randomized controlled trial; ROBINS-I: Risk of bias in non-randomised studies-of interventions.