Elastic fiber degradation in the development of pediatric granuloma annulare: Report of 39 cases

Figure 1 Elastic fiber staining was categorized into four grades according to the elastic fibers' dissolution degree and destruction. A: Grade I: Disorganized arrangement of elastic fibers in the lesion without significant dissolution (×200); B: Grade II: Partial breakage of elastic fibers in the lesion with mild dissolution (×200); C: Grade III: Partial dissolution of elastic fibers in the lesion, but small, discontinuous elastic fibers are still visible (×200); D: Grade IV: Complete dissolution and disappearance of elastic fibers in the lesion (×200).