Impact of heart failure on outcomes in patients with sepsis: A systematic review and meta-analysis

Table 2 Patient characteristics in the studies

Ref.	Sample size (M/F)	HF (n)	Disease-related score (median or range)	Sepsis mortality	Age (median or range)	Hospital/ICU LOS (days in median or range)	Mechanical ventilation	Charlson comorbidity index (median or range)
Grozdanovski et al[19]	184 (122/62)	65	N/A	95 (51.6%)	57.1 (17.9)	13 (9-20)	N/A	N/A
cui et al[9]	338 (235/103)	24	APACHEII: 14.0 (7.4); SOFA: 6.1 (4.1)	114 (33.7%)	55.8 (18.7)	14.3 (9.35)	N/A	1.2 (1.5)
Lemay et al[4]	2727 (2687/40)	713	N/A	1501 (55.0%)	76 (6.5)	N/A	661 (24.2%)	3.5 (2.6)
Mourad et al[20]	72 (32/40)	33	SAPS II: 57 (45.7-69); SOFA: 11 (9-13)	35 (48.6%)	58 (49-66)	8 (4-12.2)	30 (42%)	N/A
Vallabhajosyula et al[12]	388 (198/190)	214	APACHE-III: 83.5 (67.8-106.3); SOFA: 8.7 (6.3-11.7)	218 (56.2%)	66.5 (54.6-76.5)	N/A	213 (54.9%)	5.33 (3.33-7.67)
Abu-Kaf et al[21]	409 (210/199)	19	N/A	41 (10.02%)	31.5 (7.4)	22 (11-43)	N/A	0.29 (0.64)
Arnautovic et al[6]	109 (48/61)	89	APACHEII: 20 (15-26)	55 (50.5%)	68 (14)	8 (4-13)	73 (67%)	7 (4-9)
Schuler et al[11]	30163 (14500/4815)	19315	N/A	2847 (9.4%)	69.8 (17.1)	3.7 (2.4-6.2)	N/A	N/A
Kim et al[22]	778 (446/332)	45	SOFA: 9 (6-11)	233 (29.9%)	67 (57-74)	3.0 (0.0-8.0)	N/A	N/A
Hiraiwa et al[23]	544 (315/229)	190	SOFA: 13(11-16)	235 (43.2%)	67 (53-78)	6.7 (2.8-13.3)	217 (39.9%)	N/A

HF: Heart failure; APACHE II: Acute physiology and chronic health evaluation II; SOFA: Sequential organ failure assessment; SAPS II: Simplified acute physiology score II; ICU: Intensive care unit; LOS: Length of stay; N/A: Not available.