Association of C-reactive protein and complement factor H gene polymorphisms with risk of lupus nephritis in Chinese population

Table 7 Genotype frequencies of combined single nucleotide polymorphisms of C-reactive protein and complement factor H, n (%)

CRP-CFH genotype combination	LN	Normal	P value
rs1205 + rs1061170
CCTT	46 (17.10)	45 (14.85)	0.105
CCTC	7 (2.60)	4 (1.32)
CTTT	124 (46.10)	125 (41.25)
CTTC	14 (5.20)	31 (10.23)
TTTT	65 (24.16)	88 (29.04)
TTTC	13 (4.83)	10 (3.30)
rs3093077 + rs1061170
AATT	150 (56.39)	180 (59.80)	0.322
AATC	23 (8.65)	28 (9.30)
ACTT	81 (30.45)	71 (23.59)
ACTC	8 (3.01)	15 (4.98)
CCTT	4 (1.50)	7 (2.33)
rs3091244 + rs1061170
CCTT	133 (50.57)	155 (52.19)	0.756
CCTC	21 (7.98)	25 (8.42)
CTTT	21 (7.98)	25 (8.42)
CATT	71 (27.00)	64 (21.55)
CATC	9 (3.42)	15 (5.05)
TATT	4 (1.52)	6 (2.02)
AATT	4 (1.52)	7 (2.36)
rs1130864 + rs1061170
GGTT	208 (78.49)	228 (76.25)	0.772
GGTC	32 (12.08)	42 (14.05)
GATT	25 (9.43)	29 (9.70)
rs1800947 + rs1061170
CCTT	214 (80.75)	232 (77.85)	0.655
CCTC	30 (11.32)	41 (13.76)
CGTT	21 (7.92)	25 (8.39)
rs2794521 + rs1061170
TTTT	160 (59.93)	187 (61.92)	0.431
TTTC	26 (9.74)	35 (11.59)
TCTT	66 (24.72)	67 (22.19)
TCTC	6 (2.25)	9 (2.98)
CCTT	9 (3.37)	4 (1.32)

Pearson’s chi-squared test.

CRP: C-reactive protein; CFH: Complement factor H; LN: Lupus nephritis.