Furazolidone-induced pulmonary toxicity in Helicobacter pylori infection: Two case reports

Table 1 Summary of furazolidone-induced pulmonary hypersensitivity (literature review)

Ref.	Furazolidone administration time and dosage	Purpose of using furazolidone	Symptoms	Physical examination	Laboratory studies	Image test	Treatment
Cortez and Pankey[18], 1972	A 4 d course, 100 mg twice daily	To prevent diarrhea	Fever, dyspnea, headache, and pleuritic chest pain	Dry, crackling rales	Eosinophils elevated	Diffuse, bilateral Infiltrates (X-ray)	15 mg of prednisone orally followed by 40 mg daily
Collins and Thomas[19], 1973	A 5 d course, dose not mentioned	To treat a gastrointestinal infection	Fever, rigors, generalized rash, breathless on slight exertion, and night sweats	No abnormal physical signs	Eosinophils and ESR elevated	Diffuse mottling (X-ray)	not mentioned
Kowalski et al[20], 2005	A 10 d course, 125 mg 4 times daily	To treat Isospora Belli infection	Fever, dyspnea, and nonproductive cough	Bibasilar crackles	Eosinophil ratio elevated	Bilateral interstitial infiltrates (X-ray)	Prednisone 40 mg/day

ESR: Erythrocyte sedimentation rate.