Optimal laboratory testing protocol for patients with acne taking oral isotretinoin

Table 2 Number of patients with a laboratory abnormality by month of therapy

Laboratory	Month 1 (total number: 30), n (%)	Month 2 (total number: 26), n (%)	Month 3 (total number: 21), n (%)	Month 4 (total number: 20), n (%)	Month 5 (total number: 18), n (%)	Month 6 (total number: 13), n (%)
AST	2 (7)	2 (8)	4 (19)	1 (5)	0 (0)	1 (8)
ALT	0 (0)	1 (4)	1 (5)	1 (5)	0 (0)	1 (8)
TG	0 (0)	0 (0)	1 (5)	0 (0)	0 (0)	0 (0)
HDL	2 (7)	2 (8)	1 (5)	0 (0)	1 (6)	0 (0)
LDL	21 (70)	19 (73)	14 (67)	14 (70)	11 (61)	7 (54)
Total cholesterol	6 (20)	4 (15)	5 (24)	3 (15)	5 (28)	3 (23)

AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; TG: Triglycerides; HDL: High-density lipoprotein; LDL: Low-density lipoprotein.