Effective response to crizotinib of concurrent KIF5B-MET and MET-CDR2-rearranged non-small cell lung cancer: A case report

Figure 2 Next-generation sequencing revealed two concurrent MET fusions with different fusion partners, MET-CDR2 and KIF5B-MET. A: Images from the Integrative Genomics Viewer demonstrating the chromosomal rearrangement involving MET (chromosome 7, sequencing reads with gray background) and CDR2 (chromosome 16, sequencing reads with blue background); B: KIF5B (chromosome 10, sequencing reads with blue background). Illustrations below demonstrate the protein structure resulting from the gene fusions indicating the breakpoints of the nearby exons.