Risk of critical limb ischemia in long-term uterine cancer survivors: A population-based study

Table 4 Adjusted hazard ratios for the occurrence of critical limb ischemia in the uterine cancer survivors using a Cox proportional hazards model (n = 1889)

	Adjusted HR	95%CI	P value
Treatment modality
Surgery alone	1		0.247
Surgery with RT	1.39	(0.80-2.42)
Age at index year (yr)
< 55	1
55-65	0.72	(0.35-1.48)	0.372
65-75	2.48	(1.23-4.99)	0.011
> 75	3.63	(1.55-8.47)	0.003
Hypertension	2.18	(1.23-3.88)	0.008
HRT
0 d	1
1-30 d	0.53	(0.25-1.15)	0.108
30-180 d	1.08	(0.45-2.58)	0.864
> 180 d	3.52	(1.22-10.13)	0.020

Adjusted hazard ratios and P values were obtained from a multiple Cox model, which included treatment modality and significant explanatory variables only. UC: Uterine cancer; RT: Radiotherapy; HRT: Hormone replacement therapy; HR: Hazard ratio; CI: Confidence interval; CLI: Critical limb ischemia.