Prognostic factors for disease-free survival in postoperative patients with hepatocellular carcinoma and construction of a nomogram model

Table 3 Multivariate analysis of different factors associated with disease-free survival in hepatocellular carcinoma patients

Characteristics	HR value (95%CI)	P value
Age (yr)
< 70	1.00 (reference)
≥ 70	0.543 (0.328, 0.898)	0.017a
History of hepatitis B
Yes	1.00 (reference)
No	0.654 (0.472, 0.907)	0.011a
Hypertension
Yes	1.00 (reference)
No	0.754 (0.510, 1.114)	0.156
Cancer nodules (Single/ Multiple)
Single	1.00 (reference)
Multiple	1.009 (0.579, 1.757)	0.975
Tumor diameter (cm)
< 5	1.00 (reference)
≥ 5	1.125 (0.817, 1.548)	0.471
TNM stage
III-IV	1.00 (reference)
I-II	0.585 (0.423, 0.810)	0.001a
Portal vein thrombus
No	1.00 (reference)
Yes	1.784 (0.885, 3.597)	0.106
Fibrinogen (> 4 g/L/≤ 4 g/L)
≤ 4 g/L	1.00 (reference)
> 4 g/L	1.304 (0.872, 1.951)	0.196

^aP < 0.05.

TNM: Tumor node metastasis.