Single-cell RNA-sequencing combined with bulk RNA-sequencing analysis of peripheral blood reveals the characteristics and key immune cell genes of ulcerative colitis

Figure 6 Identification of core genes in ulcerative colitis. A: Tenfold cross validation of tuning parameter selection in the least absolute shrinkage and selection operator (LASSO) model; B: LASSO coefficient distribution of marker genes; C: Gene coefficients were screened by LASSO analysis; D-E: Receiver operating characteristic curves of LASSO-identified genes in both the training and validation sets. The area under the curve values were greater than 0.8, indicating that the model had good predictive efficacy.