Age-adjusted NT-proBNP could help in the early identification and follow-up of children at risk for severe multisystem inflammatory syndrome associated with COVID-19 (MIS-C)

Table 2 Demographic data and clinical presentation of the study population

N = 17	Results
Age (yr)2	3 (2-9)
Weight (kg)2	17 (12-34)
Gender (male)1	9 (53)
Ethnicity (white)1	14 (82)
Comorbidity1	1 (6)
Known previous COVID-19 disease (4-8 wk before)1	4 (24)
Contact with known COVID-19 case1	7 (41)
IgG antibodies to SARS-CoV-21	15 (88)
SARS-CoV-2 RT-PCR positive test1	7 (41)
Fever1	17 (100)
Days of fever2	4 (3-4)
Cutaneous rash1	7 (41)
Conjunctivitis1	7 (41)
Lymphadenopathy1	5 (29)
Palmar or plantar erythema1	3 (17)
Changes in oral mucosa1	6 (35)
Respiratory symptoms1	3 (17)
Hypoxemia1	2 (12)
SpO2 (%)2	98 (97-99)
Gastrointestinal symptoms1	10 (58)
Neurological symptoms1	3 (17)
Heart failure (age-based Ross score > 5)1	11 (65)
Cardiogenic/Vasoplegic shock1	3 (17)
Tachycardia1	13 (76)
Heart rate (bpm)2	150 (120-160)
Hypotension1	4 (23)
Systolic arterial pressure (mmHg)2	97 (75-106)
Diastolic arterial pressure (mmHg)2	60 (40-68)

¹Data presented in frequency and percentage.

²Data presented in median and interquartile range.

IgG: Immunoglobulin G; RT-PCR: Real-time polymerase chain reaction; SpO2: Oxygen saturation; bpm: Beats per minute; COVID-19: Coronavirus disease 2019; SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2.