Successful treatment of disseminated nocardiosis diagnosed by metagenomic next-generation sequencing: A case report and review of literature

Table 1 Efficacy before and after treatment

	April 25, 2020	May 23, 2020	June 16, 2020
Cough	2	1	0
Hemoptysis	20-30 mL	0	0
Dyspnea index	2	1	0
Supplemental O2 in L/min	4 L/min	2 L/min	0
Oxygenation index	265 mmHg	388 mmHg	412 mmHg

Cough index: 0: NO cough; 1: Occasionally have a cough; 2: Frequent cough, mild impact on daily life; 3: Frequent cough, serious impact on daily life. Hemoptysis volume: Small amount: < 100 mL/24 h; Moderate amount: 100-500 mL/24 h; Massive amount: > 500 mL/24 h or > 100 mL at one time. Dyspnea index: 0: Asymptomatic while climbing stairs; 1: Symptomatic while climbing stairs; 2: Symptomatic after walking 100 m on flat ground; 3: Symptomatic with the least effort (e.g., talking, getting dressed); 4: Symptomatic in bed, at rest. Oxygenation index: partial blood oxygen divided by oxygen concentration.