Early diagnostic value of liver stiffness measurement in hepatic sinusoidal obstruction syndrome induced by hematopoietic stem cell transplantation

Table 1 Revised Seattle, Baltimore, and European Society for bone marrow transplantation diagnostic criteria for hepatic sinusoidal obstruction syndrome

Standard	Definition
Revised Seattle standard	At least two of the following manifestations occurred within 20 d after HSCT: Bilirubin > 2 mg/dL, hepatomegaly with right upper abdominal pain, fluid retention, and weight gain ≥ 2% of baseline weight
Baltimore standard	At least two of the following manifestations occurred within 21 d after HSCT: Bilirubin > 2 mg/dL, hepatomegaly with right upper abdominal pain, fluid retention, and weight gain ≥ 5% of baseline weight
EBMT standard	Classic SOS: Bilirubin > 2 mg/dL within 21 d after HSCT, and at least two of the following manifestations are met: painful hepatomegaly, weight gain ≥ 5%, ascites
	Delayed type of SOS: 21 d after HSCT, there was classical SOS or SOS confirmed by pathology, or ≥ 2 classical criteria with ultrasonic or hemodynamic evidence

HSCT: Hematopoietic stem cell transplantation; SOS: Sinusoidal obstruction syndrome.