Clinical values of Barcelona Clinic Liver Cancer subgroup and up-to-7 criteria in intermediate stage hepatocellular carcinoma with transcatheter arterial chemoembolization

Table 1 General data of the patients

		All (n = 128)				OR (n = 66, 51.6%)		Non-OR (n = 62, 48.4%)			P value
		mean ± SD		n (%)		mean ± SD	n (%)	mean ± SD	n (%)
Age in yr		70.02 ± 13.04				70.48 ± 13.86		69.53 ± 12.21			0.6811
Male sex				98 (76.6)			49 (74.2)		49 (79.0)		0.5232
Viral hepatitis											0.1322
	HBV			56 (43.8)			26 (39.4)		30 (48.4)
	HCV			41 (32.0)			27 (40.9)		14 (22.6)
	HBV/HCV			4 (3.1)			1 (1.5)		3 (4.8)
	Nil			27 (21.1)			12 (18.2)		15 (24.2)
Cirrhosis, Child-Pugh											0.9852
	A			93 (72.7)			48 (72.7)		45 (72.6)
	B			35 (27.3)			18 (27.3)		17 (27.4)
Bilirubin in mg/dL		1.27 ± 0.99				1.18 ± 0.74		1.35 ± 1.20			0.3261
ALT in U/L		64.38 ± 67.61				57.91 ± 43.04		71.27 ± 86.30			0.2751
AFP as × 103 ng/mL		3.42 ± 8.86				2.52 ± 7.89		4.42 ± 6.84			0.4341
HCC number		4.20 ± 3.24				3.70 ± 2.84		4.74 ± 3.55			0.0701
HCC size in cm		7.98 ± 4.01				6.55 ± 2.98		9.50 ± 4.40			0.0011
Up-to-7 criteria											0.0012
	Within			45 (35.2)			33 (50.0)		12 (26.7)
	Beyond			83 (64.8)			33 (50.0)		50 (73.3)
Subclassification											0.0032
	B1			40 (31.3)			30 (45.5)		10 (16.1)
	B2			62 (48.4)			23 (34.8)		39 (62.9)
	B3			11 (8.6)			6 (9.1)		5 (8.1)
	B4			15 (11.7)			7 (10.6)		8 (12.9)

¹P values were analyzed with independent t test.

²Pearson’s χ² test.

AFP: Alpha-fetoprotein; ALT: Alanine aminotransferase; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma; HCV: Hepatitis C virus; OR: Objective responder; SD: Standard deviation.