Observational Study
Copyright ©The Author(s) 2022.
World J Clin Cases. Jan 14, 2022; 10(2): 563-575
Published online Jan 14, 2022. doi: 10.12998/wjcc.v10.i2.563
Table 1 Prevalence of organic disease according to clinical factors and alarm symptoms (n = 730), n (%)
Characteristics
IBS (n = 654)
Organic disease (n = 76)
P value
Female307 (46.94)27 (35.53)0.059
Onset age (yr)10.682
> 50 268 (40.98)33 (43.42)
≤ 50 386 (59.02)43 (56.58)
BMI (kg/m2)0.360
< 18.537 (5.66)1 (1.32)
18.5-23.9357 (54.59)45 (59.21)
24.0-27.9212 (32.42)26 (34.21)
≥ 2848 (7.34)4 (5.26)
Marital status0.014
Married592 (90.52)60 (78.95)
Never married46 (7.03)11 (14.47)
Divorced3 (0.46)1 (1.32)
Widowed13 (1.99)4 (5.26)
Educational level0.446
Elementary88 (13.46)13 (17.11)
Junior high school176 (26.91)14 (18.42)
High school153 (23.39)19 (25.00)
University or technical college218 (33.33)29 (30.86)
Postgraduate19 (2.91)1 (1.32)
Alcohol use0.394
Almost not488 (74.62)52 (68.42)
Previous45 (6.88)5 (6.58)
At present121 (18.50)19 (25.00)
Tobacco use0.102
Almost not456 (69.72)44 (57.89)
Previous49 (7.49)7 (9.21)
At present149 (22.78)25 (32.89)
Exercise time0.406
< 0.5 h/d154 (23.55)24 (31.58)
≥ 0.5 h/d183 (27.98)21 (27.63)
≥ 1 h/d139 (21.25)12 (17.11)
≥ 2 h/d178 (27.22)19 (25.00)
History of GI infection72 (11.01)6 (7.89)0.405
Poor sleep quality236 (36.09)26 (34.21)0.747
Dietary factor0.900
Raw or cold food131 (20.03)17 (22.37)
Spicy food258 (39.45)37 (48.68)
Lipid food119 (18.20)18 (23.68)
Milk and dairy products95 (14.53)9 (11.84)
Animal protein32 (4.89)4 (5.26)
FODMAP diet103 (15.75)12 (15.79)
Psychological self-rating scale2
Anxiety0.507
No207 (71.13)26 (70.27)
Mild52 (17.87)5 (13.51)
Moderate27 (9.28)6 (16.22)
Severe5 (1.72)0 (0)
Depression0.672
No 184 (63.23)26 (70.27)
Mild53 (18.21)4 (10.81)
Moderate43 (14.78)5 (13.51)
Severe11 (3.78)2 (5.41)
Medical expenses (RMB)0.197
< 500 yuan120 (18.35)17 (22.37)
500-1000 yuan 174 (26.61)13 (17.11)
1000-3000 yuan138 (21.10)16 (21.05)
3000-5000 yuan74 (11.31)6 (7.89)
≥ 5000 yuan148 (22.63)24 (31.58)
Rectal bleeding1115 (17.58)20 (26.32)0.063
Fecal occult blood175 (11.47)18 (23.68)0.003
Unintended weight loss (kg)1,30.003
Without507 (77.52)47 (61.84)
< 2.568 (10.40)16 (21.05)
2.5-5.040 (6.12)7 (9.21)
5.0-7.535 (5.35)3 (3.95)
≥ 7.54 (0.61)3 (3.95)
Anemia137 (5.66)11 (14.47)0.007
Fever117 (2.60)1 (1.32)0.770
Nocturnal symptoms1164 (25.08)17 (22.37)0.605
Family history of IBD, CRC or celiac disease155 (8.41)5 (6.58)0.582