Transition from minimal change disease to focal segmental glomerulosclerosis related to occupational exposure: A case report

Figure 1 Light microscopy and electron microscopy of histological changes of renal biopsy 20 years ago. A: Periodic acid-silver methenamine (PASM), × 100. No obvious lesions in renal interstitium and arterioles; B: PASM, × 400. Vacuolar degeneration of glomerular capillary basement membrane (yellow arrow), renal tubular epithelial cells vacuoles and granular degeneration (white arrow); C and D: Extensive fusion of foot process of glomerular visceral epithelial cells (C: × 6000; D: × 12000, blue arrow).