Circulating tumor DNA genomic profiling reveals the complicated olaparib-resistance mechanism in prostate cancer salvage therapy: A case report

Figure 1 Radiological and immunohistochemical results showing metastatic hormone-sensitive prostate cancer. A: Sagittal magnetic resonance imaging (MRI) showed multiple lumbar vertebrate metastases; B: Bone scanning displayed the high metabolic activity of bone lesions; C: Cross (left) and sagittal (right) sections of MRI scanning (T2WI) displayed invasion of the prostate malignant lesion into the bladder wall as well as the seminal vesicle; D: Hematoxylin-eosinstaining and immunohistochemistry results for androgen receptor, NKX3.1, and periodic Schiff Acid staining. Original magnification: 100 ×; scale bar: 100 μm. HE: Hematoxylin-eosin; AR: Androgen receptor; PSA: Periodic Schiff Acid.