Increased levels of lactate dehydrogenase and hypertension are associated with severe illness of COVID-19

Table 1 Characteristics of the patients (n = 140)

Characteristic	Mild illness (n = 114)	Severe illness (n = 26)	P value
Age (yr, %)	43.2 ± 14.0	54.7 ± 13.8	0.98
Female (n, %)	56 (49.1)	9 (34.6)	0.20
Comorbidities (n)
Hypertension	22 (19.3)	10 (38.5)	0.07
Diabetes	5 (4.4)	1 (3.8)	1.0
Chronic obstructive pulmonary disease	3 (2.6)	0	1.0
Chronic renal failure	0	2 (7.7)	1.0
Coronary heart disease	1 (0.9)	2 (7.7)	0.09
Malignant tumor	2 (1.8)	2 (7.7)	0.16
Hepatitis B	10 (8.8)	3 (11.5)	0.71
Connective tissue disease	1 (0.9)	0	0.08
Gout	2 (1.8)	1 (3.8)	0.46
Symptoms (n, %)
Fever	86 (75.4)	24 (92.3)	0.06
Cough	61 (53.5)	21 (80.8)	0.01
Expectoration	34 (29.8)	17 (65.4)	< 0.01
Fatigue	15 (13.2)	5 (19.2)	0.53
Chest pain	2 (1.8)	2 (7.7)	0.16
Myalgia	8 (7.0)	2 (7.7)	1.0
Headache	5 (4.4)	1 (3.8)	1.0
Sore throat	14 (12.3)	2 (7.7)	0.74
Shortness of breath	7 (6.1)	8 (30.8)	< 0.01
Diarrhea	12 (10.5)	2 (7.7)	1.0