Renal cell carcinoma: Evolving and emerging subtypes

Figure 1 Xp11 translocation carcinoma (hematoxylin and eosin). A: The tumor is composed of cells with clear to eosinophilic, abundant voluminous cytoplasm (× 40); B: Psammoma bodies in stromal hyaline nodules are frequently seen, but are not required for diagnosis (× 100); C: TFE3 nuclear immunohistochemical stain can assist with confirmation of the diagnosis (× 100), but can also be positive in tumors without the molecular translocation.