Morphological and electrophysiological changes of retina after different light damage in three patients: Three case reports

Figure 1 Retinal morphologic examination. A: Fundoscopy revealed an irregular scar-like lesion in the macular of the right eye; B: Autofluorescence found a heterogeneous dark signal in the macular of the right eye; C: Fluorescein angiography revealed strong fluorescence leakage around the right eye macular; D: Optical coherence tomography (OCT) revealed a deficiency in the center of the fovea; E: OCT showed retinal pigment epithelium layer breakdown and macular thinning.

Figure 2 Electrophysiological examinations of retina. A: Patent pattern visual monitoring (PVEP) examination revealed that the amplitude of P100 of PVEP was reduced in the left eye (a1, a2 and a3 correspond to stimulation frequencies of 0.5 cpd, 1 cpd and 2 cpd, respectively); B: Multi-fucus electroretinograms examination showed that the amplitude density of macular center was decreased in the left eye.

Figure 3 Retinal morphologic examinations. A-D: Funduscopic and auto-fluorescence examination revealed a black shape punctuation abnormality surrounded with a ringlike margin lesion in the right eye; E and F: Angiography (FFA + ICGA) found a macular hyper-fluorescence leakage around a black shape punctation at right eye; G: Optical coherence tomography (OCT) revealed the macular fovea thickness increased; H: OCT showed the macular cystoid edema, retinal pigment epithelium layer breakdown and choroidal neovascularization in the right eye.

Figure 4 Electrophysiological examinations of retina. A: Patent pattern visual monitoring (PVEP) examination showed that the amplitude of P100 of PVEP declined while the peak time was delayed in the right eye; B: Multi-fucus electroretinograms examination showed that the amplitude density of macular center was decreased in the right eye.

Figure 5 Retinal morphologic examinations. A and B: Funduscopic and auto-fluorescence examination revealed a blurred margin macular abnormality of the left eye; C: Optical coherence tomography showed that the macular of left eye became thinner.

Figure 6 Electrophysiological examinations of retina. Multi-fucus electroretinograms examination showed that the amplitude density of macular center was decreased in the left eye.