Wells’ syndrome possibly caused by hematologic malignancy, influenza vaccination or ibrutinib: A case report

Figure 1 Surgical image. A: Skin rash on the patient’s back at presentation; B: Skin rash on the patient’s leg at presentation.

Figure 2 Histological evidence of Wells’ syndrome in skin from the right thigh. A: Psoriasiform hyperplasia and moderately intense superficial and deep perivascular and interstitial inflammatory cell infiltrate are evident, extending into the subcutis (magnification: 40 ×); B: Eosinophilic granulocytes as the main component of the inflammatory cell infiltrate. Here, they are seen in perivascular areas but also within the interstitium between collagen bundles (magnification: 100 ×); C: Inflammatory cell infiltrate mainly composed of eosinophilic granulocytes extending into the subcutaneous fatty tissue (magnification: 200 ×).