Mixed porokeratosis with a novel mevalonate kinase gene mutation: A case report

Figure 1 Skin lesions of the patient. A: Small, brown patches on the face. B-D: Hyperkeratotic, verrucous plaques on the trunk and extremities and widespread verrucous plaques with erosions and crust on the scrotum.

Figure 2  Histopathological examination shows a cornoid lamella in the epidermis (hematoxylin-eosin staining, original magnification: ×100).

Figure 3 Analysis of the mutation in the mevalonate kinase gene. A novel mevalonate kinase missense mutation (c.155G>A) was present in the patient’s family.

Figure 4  The lesions on the patient’s scrotum were completely removed after microwave knife treatment.