Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients

Table 1 Patient’s characteristics presented as pool data and divided in two groups according to restless legs syndrome diagnosis

Variables	Patients pool data	RLS	Non-RLS	P value
n	85	23	62	-
Female/male	54/31	10/13	21/41	0.4141
Age (yr)	67.3 ± 11.4	67.8 ± 9.6	67.1 ± 12.1	0.801
95%CI	64.8 to 69.8	63.6 to 73.0	64.1 to 70.2
Weight (kg)	73.3 ± 15.9	77.3 ± 20.4	72.0 ± 14.1	0.205
95%CI		67.5 to 87.2	68.3 to 75.7
Dialysis shift morning/noon	54/31	4/19	35/27	0.0261
Years in hemodialysis	4.7 ± 5.1	5.2 ± 4.9	4.5 ± 5.2	0.592
95%CI	3.6 to 5.8	3.1 to 7.3	3.2 to 5.9
IRLS score	-	21.8 ± 6.1	-	-
95%CI		19.1 to 24.5
Iron (μg/dL)	44.7 ± 18.2	43.0 ± 16.6	45.4 ± 19.0	0.741
95%CI	38.2 to 51.2	30.2 to 55.7	37.3 to 53.4
Ferritin (ng/mL)	514.4 ± 411.7	443.7 ± 356.5	547.4 ± 441.5	0.567
95%CI	344.4 to 684.3	145.6 to 741.8	320.4 to 774.6
Hct	36.4 ± 5.3	33.9 ± 5.6	37.7 ± 4.9	0.111
95%CI	34.2 to 38.7	29.2 to 38.7	35.1 to 40.3
Hb (g/dL)	11.1 ± 1.5	10.1 ± 1.6	11.4 ± 1.4	0.022
95%CI	10.5 to 11.6	8.9 to 11.3	10.8 to 12.0
Parathormone (pmol/L)	4.9 ± 1.9	4.8 ± 1.7	4.9 ± 2.0	0.97
95%CI	4.2 to 5.5	3.6 to 6.1	4.0 to 5.8
Albumin (g/dL)	3.6 ± 0.3	3.6 ± 0.3	3.6 ± 0.3	0.853
95%CI	3.5 to 3.8	3.4 to 3.9	3.5 to 3.8
Diabetes (%)	30 (35.3)	9 (39.1)	21 (33.9)	0.7651
Hypertension (%)	30 (35.3 )	8 (34.8)	22 (35.5)	0.8321

¹For categorical data a χ² test performed. All data are mean ± SD (95%CI). IRLS: International restless legs syndrome severity scale; Hct: Hematocrit; Hb: Hemoglobin.