Outcomes of renal transplant recipients with BK virus infection and BK virus surveillance in the Auckland region from 2006 to 2012

Table 2 Univariable and multivariable Cox regression to assess potential risk factors for BK polyomavirus nephropathy

	Crude HR (+) BKVN	95%CI	P value	Adjusted HR (+) BKVN	95%CI	P value
Gender (female)	0.66	0.16-2.66	NS
Ethnicity (reference: European)
Asian	6.36	1.06-38.16	0.043	3.731	0.61-22.92	0.154
Māori/Pacific Islander	4.75	0.87-25.94	0.072	2.631	0.45-15.25	0.279
Co-morbidity
Diabetes mellitus	2.06	0.42-9.94	NS
Basiliximab induction	0.75	0.18-3.03	NS
Tacrolimus	1.64	0.44-6.11	NS
Thymoglobulin for rejection	0.03	0.00-88.65	NS
Cold ischaemia time	1.18	1.06-1.32	0.003	1.181	1.04-1.35	0.009
Acute rejection (≥ 1 episode)2	3.72	0.93-14.91	0.063	4.051	0.99-16.53	0.051
HLA mismatch	1.15	0.75-1.77	NS

¹Variables included in the multivariable Cox regression model;

²Acute rejection at any time point. HR: Hazard ratio; CI: Confidence interval; (+) BKVN: BK polyomavirus nephropathy nephropathy; HLA: Human leukocyte antigen; NS: No significance.