Immunofluorescence on paraffin embedded renal biopsies: Experience of a tertiary care center with review of literature

Table 3 Comparison of immunofluorescence intensity on fresh frozen and paraffin embedded renal biopsies

Disease	Number of cases with no difference in intensity of diagnostic immunoglobulin/complement (%) IF-F = IF-P	Number of cases with difference in intensity of diagnostic immunoglobulin/complement (%) IF-F > IF-P		Total number of cases
		Difference of 1+	Difference of 2+
IgA nephropathy	7 (78%)	2 (22%)	-	9
C-MPGN	1 (25%)	2 (50%)	1 (25%)	4
IC-MPGN	4 (100%)	-	-	4
Lupus nephritis	3 (50%)	3 (50%)	-	6
C1q nephropathy	2 (100%)	-	-	2
Membranous nephropathy	3 (43%)	3 (43%)	1 (14%)	7
Post infectious glomerulonephritis	1 (100%)	-	-	1

IF-F: Immunofluorescence on fresh frozen tissue; IF-P: Immunofluorescence on paraffin embedded tissue; C-MPGN: Complement mediated membranoproliferative glomerulonephritis; IC-MPGN: Immune complex mediated membranoproliferative glomerulonephritis.