Review
Copyright ©The Author(s) 2015.
World J Nephrol. May 6, 2015; 4(2): 169-184
Published online May 6, 2015. doi: 10.5527/wjn.v4.i2.169
Figure 4
Figure 4 Significance of inhibiting the C5-C5a receptor axis. C5 convertases formed during activation of complement cascade cleave C5 into its active products. Inhibition is feasible pharmacologically or with neutralizing antibodies. MAC: Membrane attack complex; STAT3: Signal transducers and activators of transcription 3.