Long-term outcome of ketoconazole and tacrolimus co-administration in kidney transplant patients

Table 3 Post transplant events and causes of graft loss and patient death

	Group 1(n = 199)	Group 2(n = 149)	P value
Posttransplant events, n (%)
Delayed graft function	56 (28)	39 (26)	0.77
Acute rejection	68 (34)	27 (18)	0.01
Type of rejection			0.49
Cellular rejection	49	17
Antibody rejection	14	6
Both rejections	5	4
CNI toxicity	8 (4)	15 (10)	0.09
Infectious diseases	63 (32)	54 (36)	0.37
Type of infection			0.67
CMV	32	22
BKV	14	13
HSV	5	6
Bacteria	7	10
Fungus	5	3
Total graft loss, n (%)	52 (26)	35 (23)	0.57
Causes of graft loss			0.88
DWFG	22	16
CAN	17	10
Rejection	9	5
Infection	2	3
Others	2	1
Total patient death, n (%)	27 (14)	18 (12)	0.68
Causes of death			0.88
CVD	14	10
Infections	6	5
Malignancy	2	2
Others	3	1

CNI: Calcineurin inhibitor; CMV: Cytomegalovirus; HSV: Herpes simplex virus; CVD: Cerebrovascular disease.