Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis

Table 8 Regression analysis for prediction of low bone mineral density in patients with lupus nephritis

Predictor	Odds ratio	95%CI	P value
Age	0.47	0.33-1.68	0.56
Sex	1.12	0.78-2.22	0.08
Low body mass index	1.42	0.18-1.88	0.68
Disease duration (years)	1.36	0.67-1.69	0.77
Active LN	6.95	1.89-14.21	< 0.001
Serum creatinine (μmol/L)	1.04	0.56-1.08	0.66
Glomerular filtration rate (per 10 mL/minute decrease)	0.69	0.12-2.09	0.90
Proteinuria (per 1 g/day)	1.88	0.59-3.10	0.58
Neutrophil/Lymphocyte ratio	0.41	0.36-4.92	0.71
Platelets/Lymphocytes ratio	0.68	0.71-1.04	0.89
Low C3	0.72	0.38-7.95	0.18
Low C4	0.21	0.17-2.42	0.46
Advanced LN class (III-V)	3.69	2.11-10.34	< 0.001
Fibroblast growth factor-23 (per 10 pg/mL increase)	4.18	1.49-9.90	< 0.001

LN: Lupus nephritis.