Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis

doi:10.5527/wjn.v15.i3.120318

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Sep 25, 2026; 15(3): 120318
Published online Sep 25, 2026. doi: 10.5527/wjn.v15.i3.120318

Table 4 Bone mineral density among the studied groups, n (%)/mean ± SD

Variables	Inactive LN group (n = 50)	Active LN group (n = 50)	P value
Dual-energy X-ray absorptiometry scan (g/cm²)	0.56 ± 0.16	0.42 ± 0.19	< 0.001
T score	- 0.36 ± 0.15	-1.53 ± 0.18	< 0.001
Z score	- 0.28 ± 0.14	-1.49 ± 0.22	< 0.001
Class of BMD			< 0.001
Normal BMD	37 (74)	10 (20)
Low BMD	13 (26)	40 (80)

BMD: Bone mineral density; LN: Lupus nephritis.

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Citation: Azoz NM, Ammar AA, Nafady HA, Gadelkareem RA, Abdel Aziz EM, Elzohne RA. Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis. World J Nephrol 2026; 15(3): 120318
URL: https://www.wjgnet.com/2220-6124/full/v15/i3/120318.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i3.120318

Azoz NM, Ammar AA, Nafady HA, Gadelkareem RA, Abdel Aziz EM, Elzohne RA. Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis. World J Nephrol 2026; 15(3): 120318 [DOI: 10.5527/wjn.v15.i3.120318]

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