Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis

doi:10.5527/wjn.v15.i3.120318

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Sep 25, 2026; 15(3): 120318
Published online Sep 25, 2026. doi: 10.5527/wjn.v15.i3.120318

Table 11 Receiver operating characteristic curve analysis of fibroblast growth factor-23 for the prediction of active lupus nephritis

Parameter	Value
Area under the curve	0.86
95%CI	0.78-0.94
P value	< 0.001
Optimal cutoff value, pg/mL	≥ 121.10
Sensitivity (%)	79
Specificity (%)	81
Positive predictive value (%)	80.6
Negative predictive value (%)	79.4
Accuracy (%)	80.0
Disease frequency (%)	50

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Citation: Azoz NM, Ammar AA, Nafady HA, Gadelkareem RA, Abdel Aziz EM, Elzohne RA. Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis. World J Nephrol 2026; 15(3): 120318
URL: https://www.wjgnet.com/2220-6124/full/v15/i3/120318.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i3.120318

Azoz NM, Ammar AA, Nafady HA, Gadelkareem RA, Abdel Aziz EM, Elzohne RA. Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis. World J Nephrol 2026; 15(3): 120318 [PMID: 42626256 DOI: 10.5527/wjn.v15.i3.120318]

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