Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis

doi:10.5527/wjn.v15.i3.120318

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Sep 25, 2026; 15(3): 120318
Published online Sep 25, 2026. doi: 10.5527/wjn.v15.i3.120318

Table 10 Regression analysis for the prediction of active lupus nephritis

Predictor	Odds ratio	95%CI	P value
Age	1.13	0.34-1.67	0.44
Sex	1.01	0.88-2.01	0.12
Low body mass index	0.67	0.34-1.34	0.40
Disease duration (years)	0.98	0.22-1.45	0.60
Serum creatinine (μmol/L)	0.67	0.11-1.68	0.76
Glomerular filtration rate (per 10 mL/minute decrease)	1.30	0.59-2.11	0.21
Proteinuria (per 1 g/day)	1.22	0.70-2.44	0.89
Neutrophil/Lymphocyte ratio	0.78	0.54-2.18	0.46
Platelets/Lymphocytes ratio	1.47	1.11-1.89	0.01
Low C3	1.69	1.49-1.19	0.01
Low C4	1.10	0.70-2.32	0.09
Fibroblast growth factor-23 (per 10 pg/mL increase)	2.18	1.22-4.45	< 0.001

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Citation: Azoz NM, Ammar AA, Nafady HA, Gadelkareem RA, Abdel Aziz EM, Elzohne RA. Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis. World J Nephrol 2026; 15(3): 120318
URL: https://www.wjgnet.com/2220-6124/full/v15/i3/120318.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i3.120318

Azoz NM, Ammar AA, Nafady HA, Gadelkareem RA, Abdel Aziz EM, Elzohne RA. Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis. World J Nephrol 2026; 15(3): 120318 [DOI: 10.5527/wjn.v15.i3.120318]

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