Effect of pentoxifylline on inflammatory markers in non-diabetic chronic kidney disease patients: A prospective, interventional, open label

doi:10.5527/wjn.120037

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World Journal of Nephrology

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2220-6124

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Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Sep 25, 2026; 15(3): 120037
Published online Sep 25, 2026. doi: 10.5527/wjn.120037

Table 6 Multiple regression of change in urinary protein creatinine ratio and change of mean arterial pressure, tumour necrosis factor-alpha, high-sensitivity C-reactive protein and estimated glomerular filtration rate, respectively, in group 2 over 6 months

	Unstandardized coefficients		t value	P value
	β	SE	t value	P value
MAP	-1.933	0.896	-2.159	0.046^a
hs-CRP (mg/L)	-2.909	4.734	-0.614	0.548
eGFR (mL/minute/1.73 m²)	-1.711	1.239	-1.381	0.186
TNF-α (ng/L)	-0.223	0.123	-1.817	0.088

^aP ≤ 0.05.

MAP: Mean arterial pressure; hs-CRP: High-sensitivity C-reactive protein; eGFR: Estimated glomerular filtration rate; TNF-α: Tumour necrosis factor-alpha.

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Citation: Abd El Mobdy AH, Hebah HA, Ezzat MA, Eid Mohamed BA, Ahmed FA. Effect of pentoxifylline on inflammatory markers in non-diabetic chronic kidney disease patients: A prospective, interventional, open label. World J Nephrol 2026; 15(3): 120037
URL: https://www.wjgnet.com/2220-6124/full/v15/i3/120037.htm
DOI: https://dx.doi.org/10.5527/wjn.120037

Abd El Mobdy AH, Hebah HA, Ezzat MA, Eid Mohamed BA, Ahmed FA. Effect of pentoxifylline on inflammatory markers in non-diabetic chronic kidney disease patients: A prospective, interventional, open label. World J Nephrol 2026; 15(3): 120037 [PMID: 42626272 DOI: 10.5527/wjn.120037]

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