Effect of pentoxifylline on inflammatory markers in non-diabetic chronic kidney disease patients: A prospective, interventional, open label

doi:10.5527/wjn.120037

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Sep 25, 2026; 15(3): 120037
Published online Sep 25, 2026. doi: 10.5527/wjn.120037

Table 1 Demographic data and vital signs of the studied groups, n (%) or mean ± SD

		Group 1 (n = 21)	Group 2 (n = 21)	t value¹	P value
Age (year)		52.476 ± 6.720	50.667 ± 8.593	0.760	0.452
Sex	Male	11 (52.38)	12 (57.14)	χ² = 0.096	0.757
Sex	Female	10 (47.62)	9 (42.86)	χ² = 0.096	0.757
Vital signs
SBP	Baseline	153.095 ± 17.991	146.905 ± 17.922	1.117	0.271
	After 6 months	142.857 ± 11.019	140.000 ± 12.247	0.795	0.431
	Differences	-10.238 ± 16.239	-6.905 ± 18.873
	Paired test	0.009^a	0.109
DBP	Baseline	77.143 ± 5.141	79.762 ± 5.585	-1.581	0.122
	After 6 months	75.952 ± 6.637	78.571 ± 6.353	-1.306	0.199
	Differences	-1.190 ± 9.862	-1.190 ± 8.201
	Paired test	0.586	0.514
MAP	Baseline	102.419 ± 7.284	102.114 ± 7.801	0.131	0.897
	After 6 months	98.214 ± 5.438	99.014 ± 5.588	-0.470	0.641
	Differences	-4.205 ± 9.373	-3.100 ± 10.251
	Paired test	0.053	0.181

^aP value < 0.05.

¹Students’ t-test.

SBP: Systolic blood pressure; DBP: Diastolic blood pressure; MAP: Mean arterial pressure.

Full Size Table

Citation: Abd El Mobdy AH, Hebah HA, Ezzat MA, Eid Mohamed BA, Ahmed FA. Effect of pentoxifylline on inflammatory markers in non-diabetic chronic kidney disease patients: A prospective, interventional, open label. World J Nephrol 2026; 15(3): 120037
URL: https://www.wjgnet.com/2220-6124/full/v15/i3/120037.htm
DOI: https://dx.doi.org/10.5527/wjn.120037

Abd El Mobdy AH, Hebah HA, Ezzat MA, Eid Mohamed BA, Ahmed FA. Effect of pentoxifylline on inflammatory markers in non-diabetic chronic kidney disease patients: A prospective, interventional, open label. World J Nephrol 2026; 15(3): 120037 [PMID: 42626272 DOI: 10.5527/wjn.120037]

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