Potential diagnostic role of urinary exosomal microRNAs in immunoglobulin A nephropathy: A case-control study

Table 7 Logistic regression statistics showing area under the curve of 11 important least absolute shrinkage and selection operator-selected microRNAs that can differentiate between immunoglobulin A nephropathy cases and disease controls

miRNA	hsa.miR.1224.5p	hsa.miR.1279	hsa.miR.1289	hsa.miR.20a5p.hsa.miR.20b5p	hsa.miR.32.5p	hsa.miR.365b5p	hsa.miR.4787.3p	hsa.miR.520c.3p	hsa.miR.525.3p	hsa.miR.548a3p	hsa.miR.593.3p
Accuracy (95%CI)	0.8 (0.443904537692359-0.974789273673167)	0.8 (0.443904537692359-0.974789273673167)	0.9 (0.554983882971805-0.997471421455538)	0.9 (0.554983882971805-0.997471421455538)	0.9 (0.554983882971805-0.997471421455538)	0.8 (0.443904537692359-0.974789273673167)	0.8 (0.443904537692359-0.974789273673167)	0.8 (0.443904537692359-0.974789273673167)	0.9 (0.554983882971805-0.997471421455538)	1 (0.691502892181239-1)	0.8 (0.443904537692359-0.974789273673167)
Sensitivity	0.75	0.5	0.75	0.75	0.75	0.5	0.5	0.5	0.75	1	0.5
Specificity	0.833333333	1	1	1	1	1	1	1	1	1	1
PPV	0.75	1	1	1	1	1	1	1	1	1	1
NPV	0.833333333	0.75	0.857142857	0.857142857	0.857142857	0.75	0.75	0.75	0.857142857	1	0.75
Prevalence	0.4	0.4	0.4	0.4	0.4	0.4	0.4	0.4	0.4	0.4	0.4
Detection rate	0.3	0.2	0.3	0.3	0.3	0.2	0.2	0.2	0.3	0.4	0.2
Detection prevalence	0.4	0.2	0.3	0.3	0.3	0.2	0.2	0.2	0.3	0.4	0.2
AUC (95%CI)	0.791666666666667 (0.497218723153255-1)	0.75 (0.467103566480957-1)	0.875 (0.630004501932493-1)	0.875 (0.630004501932493-1)	0.875 (0.630004501932493-1)	0.75 (0.467103566480957-1)	0.75 (0.467103566480957-1)	0.75 (0.467103566480957-1)	0.875 (0.630004501932493-1)	1 (1-1)	0.75 (0.467103566480957-1)
Kappa	0.583333333	0.545454546	0.782608696	0.782608696	0.782608696	0.545454546	0.545454546	0.545454546	0.782608696	1	0.545454546

miRNA: MicroRNA; CI: Confidence interval; PPV: Positive predictive value; NPV: Negative predictive value; AUC: Area under the receiver operating characteristic curve.