Copyright: ©Author(s) 2026.
World J Nephrol. Sep 25, 2026; 15(3): 119882
Published online Sep 25, 2026. doi: 10.5527/wjn.119882
Published online Sep 25, 2026. doi: 10.5527/wjn.119882
Table 11 Status of the 5 published microRNA markers as observed from our previous study, within 3 comparisons (immunoglobulin A nephropathy vs healthy control, disease control vs healthy control, and immunoglobulin A nephropathy vs disease control)
| IgA nephropathy vs healthy control | ||||
| Probe name | Nephropathy | Control | Ig A nephropathy vs healthy control | P-value of: Nephropathy vs control |
| hsa-miR-146b-3p | 4.07 | 13.3 | -3.27 | 0.00047341 |
| hsa-miR-221-5p | 8.72 | 14.66 | -1.68 | 0.00512936 |
| hsa-miR-4532 | 7.01 | 12.3 | -1.76 | 0.00655229 |
| hsa-miR-599 | 7.26 | 16.63 | -2.29 | 0.00649493 |
| hsa-miR-664b-5p | 3.85 | 9.47 | -2.46 | 0.00083272 |
| IgA nephropathy vs disease control | ||||
| Probe name | Nephropathy | Disease control | IgA nephropathy vs disease control | P-value of: Nephropathy vs disease control |
| hsa-miR-146b-3p | 6.17 | 8.4 | -1.36 | 0.26787862 |
| hsa-miR-221-5p | 11.35 | 11.84 | -1.04 | 0.73601639 |
| hsa-miR-4532* | 8.79 | 21.09 | -2.4 | 0.04225222 |
| hsa-miR-599 | 8.66 | 10.01 | -1.16 | 0.5314607 |
| hsa-miR-664b-5p | 5.45 | 5.32 | 1.02 | 0.87722093 |
| Disease control vs healthy control | ||||
| Probe name | Disease control | Control | Disease control vs healthy control | P-value of: Disease control vs healthy control |
| hsa-miR-146b-3p | 8.4 | 15.41 | -1.83 | 0.04495602 |
| hsa-miR-221-5p | 11.84 | 18.22 | -1.54 | 0.00787352 |
| hsa-miR-4532 | 21.09 | 18.09 | 1.17 | 0.68054599 |
| hsa-miR-599 | 10.01 | 18.5 | -1.85 | 0.03426054 |
| hsa-miR-664b-5p | 5.32 | 9.86 | -1.85 | 0.0062102 |
- Citation: Shankar M, Moorthy M, Shetty A, Gurusiddaiah SC. Potential diagnostic role of urinary exosomal microRNAs in immunoglobulin A nephropathy: A case-control study. World J Nephrol 2026; 15(3): 119882
- URL: https://www.wjgnet.com/2220-6124/full/v15/i3/119882.htm
- DOI: https://dx.doi.org/10.5527/wjn.119882