Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis

Figure 1 Receiver operating characteristic curves for acute kidney injury biomarker performance. Receiver operating characteristic curves comparing the diagnostic accuracy of neutrophil gelatinase-associated lipocalin, cystatin C, renal resistive index, and serum creatinine in detecting acute kidney injury. Areas under the curve with 95%CI: (1) Neutrophil gelatinase-associated lipocalin = 0.91 (0.87-0.95); (2) Renal resistive index = 0.89 (0.83-0.94); (3) Cystatin C = 0.86 (0.81-0.91); and (4) Creatinine = 0.73 (0.66-0.80). The diagonal dashed line represents chance-level discrimination (area under the curve = 0.5). AKI: Acute kidney injury; AUC: Areas under the curve; NGAL: Neutrophil gelatinase-associated lipocalin; ROC: Receiver operating characteristic; RRI: Renal resistive index.