Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis

doi:10.5527/wjn.119581

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Sep 25, 2026; 15(3): 119581
Published online Sep 25, 2026. doi: 10.5527/wjn.119581

Table 3 Specialized tests by acute kidney injury subtype, mean ± SD

Test	Pre-renal acute kidney injury (n = 43)	Hepatorenal syndrome (n = 20)	Acute tubular necrosis (n = 15)	P value
Granular casts ≥ 5/high-power field	0% (0/43)	0% (0/20)	100% (15/15)	< 0.001
Renin (ng/mL)	5.8 ± 2.1	12.1 ± 4.0	6.3 ± 2.4	0.01
Aldosterone (pg/mL)	98 ± 32	240 ± 68	112 ± 44	0.03

P < 0.05 vs pre-renal acute kidney injury using Kruskal-Wallis and Dunn’s correction.

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Citation: Othman AAA, Mohamed MM, Eladl MM, Elsayed FMA. Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis. World J Nephrol 2026; 15(3): 119581
URL: https://www.wjgnet.com/2220-6124/full/v15/i3/119581.htm
DOI: https://dx.doi.org/10.5527/wjn.119581

Othman AAA, Mohamed MM, Eladl MM, Elsayed FMA. Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis. World J Nephrol 2026; 15(3): 119581 [PMID: 42626007 DOI: 10.5527/wjn.119581]

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