Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis

doi:10.5527/wjn.119581

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Sep 25, 2026; 15(3): 119581
Published online Sep 25, 2026. doi: 10.5527/wjn.119581

Table 2 Biomarker accuracy for acute kidney injury detection

Marker	Area under the curve (95%CI)	Cutoff	Sensitivity (%) (95%CI)	Specificity (%) (95%CI)
Neutrophil gelatinase-associated lipocalin	0.91 (0.87-0.95)	> 150 ng/mL	90 (85-94)	85 (78-90)
Cystatin C	0.86 (0.81-0.91)	> 1.5 mg/L	84 (77-89)	80 (72-86)
Renal resistive index	0.89 (0.83-0.94)	> 0.74	82 (74-88)	88 (81-93)
Creatinine	0.73 (0.66-0.80)	> 1.2 mg/dL	68 (60-76)	62 (54-70)

Sensitivity and specificity values are provided with their 95%CI.

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Citation: Othman AAA, Mohamed MM, Eladl MM, Elsayed FMA. Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis. World J Nephrol 2026; 15(3): 119581
URL: https://www.wjgnet.com/2220-6124/full/v15/i3/119581.htm
DOI: https://dx.doi.org/10.5527/wjn.119581

Othman AAA, Mohamed MM, Eladl MM, Elsayed FMA. Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis. World J Nephrol 2026; 15(3): 119581 [PMID: 42626007 DOI: 10.5527/wjn.119581]

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