Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis

doi:10.5527/wjn.119581

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Sep 25, 2026; 15(3): 119581
Published online Sep 25, 2026. doi: 10.5527/wjn.119581

Table 10 Net clinical benefit of neutrophil gelatinase-associated lipocalin - renal resistive index vs creatinine at selected thresholds

Threshold probability	Neutrophil gelatinase-associated lipocalin-renal resistive index net benefit	Creatinine net benefit
10%	0.12	0.04
25%	0.18	0.06
40%	0.20	0.08

Net benefit is calculated as (true positives - weighted false positives)/total patients. Higher values indicate better clinical decision-making utility.

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Citation: Othman AAA, Mohamed MM, Eladl MM, Elsayed FMA. Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis. World J Nephrol 2026; 15(3): 119581
URL: https://www.wjgnet.com/2220-6124/full/v15/i3/119581.htm
DOI: https://dx.doi.org/10.5527/wjn.119581

Othman AAA, Mohamed MM, Eladl MM, Elsayed FMA. Integrated biomarkers and renal Doppler for early acute kidney injury diagnosis in hepatitis C virus cirrhosis. World J Nephrol 2026; 15(3): 119581 [PMID: 42626007 DOI: 10.5527/wjn.119581]

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