Is the metabolic dysfunction-associated steatotic liver disease a predictor of chronic kidney disease?

doi:10.5527/wjn.v15.i2.118877

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World Journal of Nephrology

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2220-6124

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World J Nephrol. Jun 25, 2026; 15(2): 118877
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.118877

Table 7 Multivariate regression analysis of the risk factors of chronic kidney disease in patients with metabolic dysfunction-associated steatotic liver disease

Variables	Odds ratio	95%CI	P value
Old age (years)	1.19	0.45-2.78	0.402
Sex	1.03	0.90-3.14	0.316
Obesity	2.37	1.67-7.89	0.012
Diabetes mellitus	3.10	2.39-8.19	< 0.001
PLR (> 150)	2.90	1.18-5.17	0.010
NLR (> 3)	2.17	1.22-6.01	< 0.001
HOMA-IR	4.15	2.90-11.19	< 0.001
FIB-4 (> 3.25)	3.56	2.78-9.18	< 0.001
Fibrosis score > F2	5.61	3.45-13.90	< 0.001
Steatosis score > S3	4.17	2.23-10.56	< 0.001

CI: Confidence interval; FIB-4: Fibrosis-4 index; HOMA-IR: Homeostasis Model Assessment of Insulin Resistance; NLR: Neutrophil/Lymphocyte ratio; PLR: Platelets/Lymphocyte ratio; F: Fibrosis; S: Steatosis.

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Citation: Azoz NM, Shehata MA, Abbas WA, Gadelkareem RA, Abdel Aziz EM. Is the metabolic dysfunction-associated steatotic liver disease a predictor of chronic kidney disease? World J Nephrol 2026; 15(2): 118877
URL: https://www.wjgnet.com/2220-6124/full/v15/i2/118877.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i2.118877

Azoz NM, Shehata MA, Abbas WA, Gadelkareem RA, Abdel Aziz EM. Is the metabolic dysfunction-associated steatotic liver disease a predictor of chronic kidney disease? World J Nephrol 2026; 15(2): 118877 [PMID: 42395676 DOI: 10.5527/wjn.v15.i2.118877]

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