Is the metabolic dysfunction-associated steatotic liver disease a predictor of chronic kidney disease?

doi:10.5527/wjn.v15.i2.118877

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World Journal of Nephrology

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2220-6124

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Jun 25, 2026; 15(2): 118877
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.118877

Table 2 Demographic and baseline clinical characteristics of patients and control groups, mean ± SD/n (%)

Variables	MASLD with DM (n = 50)	MASLD without DM (n = 50)	Control group (n = 50)	P value
Age (years)	46.53 ± 3.89	42.65 ± 13.90	43.98 ± 12.01	0.104
Sex				0.550
Male	34 (68)	38 (74)	37 (74)
Female	16 (32)	12 (24)	13 (26)
BMI (kg/m²)	28.18 ± 3.22	27.01 ± 4.30	22.10 ± 3.33	< 0.001
Residence				0.511
Rural	30 (60)	34 (68)	35 (70)
Urban	20 (40)	16 (32)	15 (30)
Smoking status				0.856
Smoker	9 (18)	10 (20)	12 (24)
Ex-smoker	15 (30)	15 (30)	8 (16)
Passive smoker	7 (14)	10 (20)	9 (18)
None	19 (38)	15 (30)	21 (42)
Hypertension	12 (24)	3 (6)	0	< 0.001
IHD	2 (4)	0	0	< 0.001
Pulse (b/minute)	83.09 ± 12.45	80.09 ± 10.34	80 ± 8.76	0.406
SBP (mmHg)	121.76 ± 18.89	118.90 ± 22.18	117 ± 14.67	0.076
DBP (mmHg)	75.40 ± 8.55	71.18 ± 7.19	70.13 ± 6.66	0.562

BMI: Body mass index; DBP: Diastolic blood pressure; DM: Diabetes mellitus; IHD: Ischemic heart disease; MASLD: Metabolic dysfunction-associated steatotic disease; SBP: Systolic blood pressure.

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Citation: Azoz NM, Shehata MA, Abbas WA, Gadelkareem RA, Abdel Aziz EM. Is the metabolic dysfunction-associated steatotic liver disease a predictor of chronic kidney disease? World J Nephrol 2026; 15(2): 118877
URL: https://www.wjgnet.com/2220-6124/full/v15/i2/118877.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i2.118877

Azoz NM, Shehata MA, Abbas WA, Gadelkareem RA, Abdel Aziz EM. Is the metabolic dysfunction-associated steatotic liver disease a predictor of chronic kidney disease? World J Nephrol 2026; 15(2): 118877 [PMID: 42395676 DOI: 10.5527/wjn.v15.i2.118877]

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