Critical care considerations in rhabdomyolysis-associated acute kidney injury and kidney replacement therapy

Table 3 Summary of management strategies of rhabdomyolysis-associated acute kidney injury

Management therapy	Recommendation
Fluid resuscitation	Early initiation; use crystalloids (lactated Ringer’s or normal saline); volume of 6 L/day or more
Bicarbonate, mannitol and antioxidant use	Based on clinician’s judgement; limited evidence with little difference in outcomes
Monitoring	Electrolyte imbalances: Hyperkalemia, hyperphosphatemia, hypocalcemia, hypomagnesemia; hemodynamic monitoring: Mean arterial pressure, renal perfusion pressure
Diuretics	Not necessary, except in fluid overload