Glomerulonephritis through the lens of ultrasound and radiology

doi:10.5527/wjn.v15.i2.118229

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World Journal of Nephrology

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2220-6124

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Jun 25, 2026; 15(2): 118229
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.118229

Table 2 Practical ultrasound features in differentiating acute vs chronic glomerulonephritis¹

Parameter	Acute GN/AKI	Chronic GN/CKD	Key differentiating feature
Kidney size	Normal or enlarged	Decreased renal length (< 8 cm)	Enlarged = acute; small = chronic
Cortical thickness	May be normal or increased	Reduced	Thinning indicates chronic damage
Echogenicity	Increased (infiltrates/edema)	Increased (fibrosis/sclerosis)	Alone non-specific; paired with size aids differential diagnosis
Corticomedullary differentiation	May be increased, Preserved or increased	Often reduced or lost	Loss of differentiation implies chronicity

¹Reported thresholds are protocol dependent and may vary according to acquisition settings and patient population.

AKI: Acute kidney injury; CKD: Chronic kidney disease; GN: Glomerulonephritis.

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Citation: Gembillo G, Silipigni S, Sessa C, Lo Cicero L, Soraci L, Cozza A, Bruccoleri R, Peritore L, Morale W, Corsonello A, Bottari A, Santoro D. Glomerulonephritis through the lens of ultrasound and radiology. World J Nephrol 2026; 15(2): 118229
URL: https://www.wjgnet.com/2220-6124/full/v15/i2/118229.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i2.118229

Gembillo G, Silipigni S, Sessa C, Lo Cicero L, Soraci L, Cozza A, Bruccoleri R, Peritore L, Morale W, Corsonello A, Bottari A, Santoro D. Glomerulonephritis through the lens of ultrasound and radiology. World J Nephrol 2026; 15(2): 118229 [PMID: 42395682 DOI: 10.5527/wjn.v15.i2.118229]

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