Glomerulonephritis through the lens of ultrasound and radiology

doi:10.5527/wjn.v15.i2.118229

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Jun 25, 2026; 15(2): 118229
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.118229

Table 1 Prognostic significance of key ultrasound morphologic parameters in glomerulonephritis

Parameter¹	Typical US finding	Correlation with histology	Predictive value²
Renal echogenicity	Increased cortical echogenicity (grades II-IV)	Glomerulosclerosis, tubulointerstitial fibrosis, inflammation	Higher echogenicity correlates with lower eGFR
Cortical thickness	Decreased cortical thickness	Positive correlation with eGFR	< 4.0 mm/cm predicts > 30% eGFR decline or dialysis initiation (sensitivity 72.5%, specificity 80%)

¹Renal cortical thickness normalized for patient height: Cortical thickness (mm) divided by height (cm).

²Reported cut-off values are protocol dependent and may vary according to acquisition settings and patient population.

eGFR: Estimated glomerular filtration rate; US: Ultrasound.

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Citation: Gembillo G, Silipigni S, Sessa C, Lo Cicero L, Soraci L, Cozza A, Bruccoleri R, Peritore L, Morale W, Corsonello A, Bottari A, Santoro D. Glomerulonephritis through the lens of ultrasound and radiology. World J Nephrol 2026; 15(2): 118229
URL: https://www.wjgnet.com/2220-6124/full/v15/i2/118229.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i2.118229

Gembillo G, Silipigni S, Sessa C, Lo Cicero L, Soraci L, Cozza A, Bruccoleri R, Peritore L, Morale W, Corsonello A, Bottari A, Santoro D. Glomerulonephritis through the lens of ultrasound and radiology. World J Nephrol 2026; 15(2): 118229 [PMID: 42395682 DOI: 10.5527/wjn.v15.i2.118229]

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