Pediatric cardiac surgery associated-acute kidney injury: Interleukin 18 as a new biomarker

doi:10.5527/wjn.v15.i2.117015

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World Journal of Nephrology

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2220-6124

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Jun 25, 2026; 15(2): 117015
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.117015

Table 3 Comparison of interleukin 18 at different time points in those with and without cardiac surgery associated acute kidney injury

Renal biomarker at time points (hours)	Cardiac surgery associated acute kidney injury		P value
Renal biomarker at time points (hours)	Present (n = 7)	Absent (n = 33)	P value
0	13.36 ± 4.05	12.72 ± 5.27	0.727
4	26.73 ± 3.44	17.47 ± 6.45	0.001^a
8	40.02 ± 6.52	18.35 ± 7.16	0.000^a
12	29.61 ± 5.37	17.96 ± 6.06	0.002^a
24	24.68 ± 4.50	16.72 ± 5.54	0.000^a
48	22.98 ± 3.27	14.95 ± 4.98	0.000^a

^aP ≤ 0.05 significant.

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Citation: Makinde RA, Ajose AO, Ajeigbe AK, Adedeji TA, Onakpoya UU, Ojo OO. Pediatric cardiac surgery associated-acute kidney injury: Interleukin 18 as a new biomarker. World J Nephrol 2026; 15(2): 117015
URL: https://www.wjgnet.com/2220-6124/full/v15/i2/117015.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i2.117015

Makinde RA, Ajose AO, Ajeigbe AK, Adedeji TA, Onakpoya UU, Ojo OO. Pediatric cardiac surgery associated-acute kidney injury: Interleukin 18 as a new biomarker. World J Nephrol 2026; 15(2): 117015 [PMID: 42395673 DOI: 10.5527/wjn.v15.i2.117015]

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